Biopharmaceuticals

From early-stage screening to formulation development, driving innovation in the biopharmaceutical field.

The advancement of optical technologies has introduced powerful tools for cost reduction and efficiency enhancement in the biopharmaceutical field.

In biopharmaceutical R&D and production, stringent particulate matter control is essential. The PartiGen particulate matter detector, combined with the XtremSig-P chip, enables precise detection and tracing of particulate contaminants in pharmaceutical formulations, ensuring product quality.

In drug development, the establishment of stable cell lines is critical for protein drug production,target screening, and toxicity assessment. Traditional methods often suffer from long screening cycles and low cell viability. HOOKE's visual single-cell sorting technology platform significantly shortens the stable cell line development process through precise screening.

Additionally, the S3000 Ultra-fast 3D fluorescence imaging system provides high-resolution, ultra-fast confocal imaging, serving as a powerful tool for drug research and development.

Exploration

Biopharmaceutical Particulate Matter Analysis Solution

The PartiGen Particle Analyzer integrates high-precision image recognition, high-sensitivity Raman detection, and advanced database search capabilities. Utilizing confocal Raman spectroscopy, it enables particle size analysis and components identification of particulate matter in biopharmaceutical samples. With an integrated bio-pharmaceutical-specific spectral database, it supports pharmaceutical R&D and manufacturing, providing reliable data for process optimization, quality control and regulatory compliance.

Visualized Single-Cell Sorting Solution

Utilizing laser-induced forward transfer (LIFT), optical tweezers, and other advanced technologies, which features a unique visualized sorting capability, enabling precise single-cell sorting under a microscope. The non-contact separation approach effectively preserves cell viability, ensuring highly efficient cultivation of isolated cells. The platform seamlessly integrates with multi-channel fluorescence imaging, confocal Raman spectroscopy, and other phenotypic detection systems, meeting diverse cell identification and screening needs while accelerating the process of stable cell line selection.

3D Fluorescence Imaging Platform

The S3000 Ultra-Fast 3D Fluorescence Imaging System utilizes spinning disk confocal imaging technology combined with high-speed motorized Z-axis scanning, accelerating imaging by at least 20 times. Equipped with an LED area light source, it ensures more uniform excitation while significantly reducing phototoxicity and photobleaching, making it ideal for dynamic continuous observation. This system provides an ultra-fast 3D imaging tool for research in drug target localization, drug delivery systems, and cell and gene therapy, greatly enhancing research and development efficiency.