P300
Confocal Raman Microscope
A professional research-grade Raman spectroscopy system designed for rapid, efficient, and highly sensitive detection of weak Raman signals. It employs multi-dimensional calibration to ensure data stability and features intelligent analysis software for in-depth spectral interpretation. The P300 provides advanced solutions for life sciences, medical research, environmental science, food safety, chemistry, and materials science, supporting the development of the label-free and non-invasive detection technologies.
Brochures
Advantages
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Efficient Weak Raman Signal Collection
To ensure effective acquisition of weak signals from tiny samples and reduce acquisition time, the system employs a three-mirror optical design with a single-piece high-transmittance reflective coating, achieving a reflectivity of ≥98% and enhancing overall optical throughput by more than 30%.
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Multi-Dimensional Spectral Calibration System
The system features a unique built-in multi-dimensional calibration mechanism, ensuring exceptional data reproducibility. With spectral stability better than 0.01 cm⁻¹, it meets the high-quality data requirements for spectral database construction.
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Intelligent Visual Data Analysis
Integrating spectral processing, clustering, and classification functions, the system provides a visual index for streamlined and intuitive Raman data interpretation, making in-depth spectral analysis more accessible.
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Database Building & Rapid Retrieval
Offers a self-built database creation process with customizable sample labeling, enabling fast and intelligent spectral search and retrieval.
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Automated Batch Detection
Utilizing morphological reconstruction and multi-field continuous scanning technology, the system enables fully automated identification, localization, and detection of target objects, achieving true unattended operation.
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Raman+ Series Products
Optional optical tweezers manipulation and sorting module enables the acquisition of target cells for downstream sequencing or cultivation studies,beyound cell phenotyping analysis.
Working Principle
The P300 utilizes laser confocal technology and Raman spectroscopy principles, emitting specific wavelength laser light through a high-sensitivity laser to irradiate the sample and excite Raman scattering. It features an integrated multi-dimensional calibration system that calibrates peak intensity, peak position, background noise, and other parameters, ensuring high reproducibility and stability of spectral data.


Applications
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Medical Research
Phenotypic detection combined with single-cell analysis enhances detection speed and accuracy, driving advancements in medical research.
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Biopharmaceuticals
From early-stage screening to formulation development, driving innovation in the biopharmaceutical field.
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Microbiology
Addressing the research challenge of uncultured microorganisms through a multidimensional and multiscale research platform.
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Fermentation Broth Testing
The integration of AI morphology analysis and Raman spectroscopy technology drives innovation in fermentation broth detection techniques.
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Microplastics
From environment to biological samples, rapid identification of microplastics in various samples.
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Medical Research
Phenotypic detection combined with single-cell analysis enhances detection speed and accuracy, driving advancements in medical research.
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Biopharmaceuticals
From early-stage screening to formulation development, driving innovation in the biopharmaceutical field.
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Microbiology
Addressing the research challenge of uncultured microorganisms through a multidimensional and multiscale research platform.
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Fermentation Broth Testing
The integration of AI morphology analysis and Raman spectroscopy technology drives innovation in fermentation broth detection techniques.
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Microplastics
From environment to biological samples, rapid identification of microplastics in various samples.
Publications
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International Journal of Biological Macromolecules|Injectable chitosan-polyvinylpyrrolidone composite thermosensitive hydrogels with sustained submucosal lifting for endoscopic submucosal dissection2024.07.16
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Analyst|Evaluation of Raman spectroscopy combined with the gated recurrent unit serum detection method in early screening of gastrointestinal cancer2024.06.04
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European Polymer Journal|Chitosan with enhanced deprotonation for accelerated thermosensitive gelation with β-glycerophosphate2024.05.15
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Microbial Biotechnology|Rapid detection of six Oceanobacillus species in Daqu starter using single-cell Raman spectroscopy combined with machine learning2024.04.03
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AAPS PHARMSCITECH|Visible Particle Identifcation Using Raman Spectroscopy and Machine Learning2024.03.16
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ACS ES&T Water|Phosphorus Removal and Storage Polymer Synthesis by Tetrasphaera-Related Bacteria with Different Carbon Sources2023.05.15
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Frontiers in Microbiology|Rapid identification and drug resistance screening of respiratory pathogens based on single-cell Raman spectroscopy2023.02.03
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Computational and Structural Biotechnology Journal|Building an ensemble learning model for gastric cancer cell line classification via rapid Raman spectroscopy2023.01.12
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Journal of Biophotonics|Classification of pathogenic bacteria by Raman spectroscopy combined with variational auto-encoder and deep learning2023.01.09
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Analytical Methods|Stain-free Gram staining classification of pathogens via single-cell Raman spectroscopy combined with machine learning2022.10.31
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Advanced Science|Evidence and Impacts of Nanoplastic Accumulation on Crop Grains2022.10.28
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Materials|Microstructure Evolution and Performance Improvement of Silicon Carbide Ceramics via Impregnation Method2022.08.30
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Frontiers in Microbiology|Single Cell Raman Spectroscopy Deuterium Isotope Probing for Rapid Antimicrobial Susceptibility Test of Elizabethkingia spp2022.06.02
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Analytical Chemistry|Classification and Identification of Archaea Using Single-Cell Raman Ejection and Artificial Intelligence: Implications for Investigating Uncultivated Microorganisms2022.01.18
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Advanced Healthcare Materials|Unraveling an Innate Mechanism of Pathological Mineralization-Regulated Inflammation by a Nanobiomimetic System2021.10.13
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Ceramics International|Properties regulation of SiC ceramics prepared via stereolithography combined with reactive melt infiltration techniques2021.09.17
Configuration List
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Core Module
532 nm confocal Raman spectrometer
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Optional
Identification
Fluorescence module
Single-cell Sorter
LIFT, Optical tweezers
Consumable
XtremSig™ Ultra-Low Background Raman Detection Chip
Accessories
Clean Benches, Biological Safety Cabinets, Anaerobic Chamber,Active Vibration Isolation Table,